CPT1C Antikörper (AA 121-170)

Produktnummer ABIN1386084

Dieser Anti-CPT1C Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CPT1C in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Geeignet für Human.

Kurzübersicht für CPT1C Antikörper (AA 121-170) (ABIN1386084)

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-CPT1C Antikörper

Bindungsspezifität: AA 121-170

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cpt1c

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Andere Bezeichnung: Cpt1c

Hintergrund:

Synonyms: CPT1-C, Carnitine acyltransferase like protein 1, Carnitine acyltransferase like protein1, Carnitine O palmitoyltransferase I, brain isoform, Carnitine palmitoyltransferase 1, brain, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase I related C, Carnitine palmitoyltransferase1C, CAT L1, CATL 1, CATL1, CPT 1 like pseudogene, Cpt 1c, CPT 1P, CPT I C, Cpt1 c, CPT1 like pseudogene, CPT1P , CPTIC.CPT1C_HUMAN

Background: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

Gen-ID: 126129

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process